Living Well after Breast Cancer
The NHMRC-funded Living Well after Breast Cancer study is a randomised controlled trial which aims to evaluate a telephone-delivered weight loss intervention compared to usual care for overweight and obese women who have recently completed treatment for breast cancer.
The study commenced in 2012. A total of 160 women (80 per group) were recruited into the study via the Queensland Cancer Registry and Brisbane hospitals. Data collection occurs at baseline, 6-, 12- and 18-months in order to evaluate the weight loss intervention (compared to usual care) on its ability to promote and maintain weight loss, and to improve body composition, physical activity, dietary intake, clinical biomarkers of metabolic health, genomic and DNA methylation-based biomarkers, blood pressure and patient-reported outcomes. Women allocated to the intervention group receive up to 22 telephone calls from a Lifestyle Coach over 12 months along with a detailed workbook, set of digital scales, measuring tape, pedometer, kilojoule/calorie counter book, self-monitoring diary, and detailed written feedback from each assessment. During their telephone calls the Lifestyle Coach will help the participant to set small goals around increasing physical activity and healthy eating to achieve a weight loss of 5-10 per cent of their initial body weight. Women allocated to the usual care group are posted a study newsletter, a copy of Breast Cancer Network Australia’s Beacon magazine, and brief written feedback from each assessment every 6-months. They continue to receive standard care from their treating clinicians throughout the study. Final data collection will occur in mid-2016.